Welcome to my educational journey. Below, you will find details about my academic qualifications and achievements:
Faculty of Pharmacy of the University of Porto (Portugal)
Institute of Biomedical Sciences Abel Salazar (Portugal)
Final grade: 18 (out of 20)
Dissertation grade: 19
Faculty of Sciences of the University of Porto (Portugal)
Final grade: 14.45 (out of 20)
Internship grade: 19
Welcome to my academic research journey. Below, you'll find an overview of my research experience and the places and projects in which I've worked:
Instituto de Investigação e Inovação em Saúde (i3S - Cancer Drug Resistance Group)
I was awarded a PhD scholarship by the Fundação para a Ciência e Tecnologia (FCT). My PhD project focused on evaluating the activity of novel Isoquinolinequinone N-oxides against multidrug-resistant tumors. This involved investigating the mechanisms of action in both in vitro 2D cell models and 3D cell models, specifically in spheroids composed of triple cultures of fibroblasts, macrophages, and tumor cells.
Interdisciplinary Centre of Marine and Environmental Research (CIIMAR - Endocrine disruptors and emergent contaminants' Laboratory)
I conducted in vitro and in vivo assays (using zebrafish larvae) to assess the toxic effects and mechanisms of action of tributyltin and wastewater treatment plant effluents on obesity and lipid homeostasis. Upon completing my master's thesis, I was invited by my group leader and supervisor to continue with the team as a research technician. In this role, I carried out further research on the project and managed various laboratory tasks, including stock verification and product quotation requests.
Instituto de Investigação e Inovação em Saúde (i3S - Cancer Drug Resistance Group)
I was selected for a Master fellowship position, where I processed blood samples from patients with Multiple Myeloma. In this project, I isolated and characterized extracellular vesicles collected non-invasively from liquid biopsies and investigated the presence of Minimal Residual Disease biomarkers.
Interdisciplinary Centre of Marine and Environmental Research (CIIMAR - Endocrine disruptors and emergent contaminants' Laboratory)
I conducted in vitro and in vivo assays (using zebrafish larvae) to assess the toxic effects and mechanisms of action of tributyltin and wastewater treatment plant effluents on obesity and lipid homeostasis. Upon completing my master's thesis, I was invited by my group leader and supervisor to continue with the team as a research technician. In this role, I carried out further research on the project and managed various laboratory tasks, including stock verification and product quotation requests.
Faculty of Sciences of the University of Porto (Aerobiology Group)
In this project, I performed in vitro assays in which I assessed the effects of ozone on the germination, viability and allergenic potential of Pinus spp. pollen.
In this section you'll find an overview of my scientific research publications in peer-reviewed Q1 journals from the various projects and collaborations in which I have been involved:
"Discovery of Potent Isoquinolinequinone N-oxides to Overcome Cancer Multidrug Resistance"
Year: 2024
Impact factor (current): 7.3
Type of participation: First author
Type of publication: Original paper
Status of publication: Under review
"Detection of Measurable Residual Disease Biomarkers in Extracellular Vesicles from Liquid Biopsies of Multiple Myeloma Patients—A Proof of Concept"
Year: 2022
Impact factor (2022): 5.6
Type of participation: Co-author
Type of publication: Original paper
Status of publication: Published
"3D cell culture models as recapitulators of the tumor microenvironment for the screening of anti-cancer drugs"
Year: 2021
Impact factor (2021): 6.6
Type of participation: First author
Type of publication: Review
Status of publication: Published
Selected as one of “Highly Cited Papers and Hot Topic Special Issues on Anti-cancer Research” by Cancers (MDPI) in 2023
"The role of extracellular vesicles in the hallmarks of cancer and drug resistance"
Year: 2020
Impact factor (2020): 7.6
Type of participation: Co-author
Type of publication: Review
Status of publication: Published
"Linking chemical exposure to lipid homeostasis: A municipal waste water treatment plant influent is obesogenic for zebrafish larvae"
Year: 2019
Impact factor (2019): 4.8
Type of participation: First author
Type of publication: Original paper
Status of publication: Published
Awarded by the IACOBUS Program 2019 - “Scientific Publications”
"Evolutionary exploitation of vertebrate peroxisome proliferator-activated receptor γ by organotins"
Year: 2018
Impact factor (2018): 7.1
Type of participation: Co-author
Type of publication: Original paper
Status of publication: Published